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Characterization of CD4+ T cell subsets and HIV susceptibility in the inner and outer foreskin of Ugandan men

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Biological mechanisms of foreskin HIV acquisition are poorly defined. The inner foreskin is preferentially infected in explant models, so we hypothesized that this site would be enriched for HIV‐susceptible CD4+… Click to show full abstract

Biological mechanisms of foreskin HIV acquisition are poorly defined. The inner foreskin is preferentially infected in explant models, so we hypothesized that this site would be enriched for HIV‐susceptible CD4+ T cells and proinflammatory/chemoattractant cytokines.

Keywords: cell subsets; hiv susceptibility; characterization cd4; subsets hiv; cd4; cd4 cell

Journal Title: American Journal of Reproductive Immunology
Year Published: 2019

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