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Pregnancy remains an immune challenge for the uterus that has to adapt to a semi‐allogeneic fetus using various regulatory mechanisms. Both HLA‐G and regulatory T cells (CD4+ CD25+ FOXP3+ Tregs)… Click to show full abstract
Pregnancy remains an immune challenge for the uterus that has to adapt to a semi‐allogeneic fetus using various regulatory mechanisms. Both HLA‐G and regulatory T cells (CD4+ CD25+ FOXP3+ Tregs) are upregulated in successful pregnancy, but not in abortion. It is unclear if HLA‐G plays a role in the upregulation of regulatory cells.
Keywords:
hla induction;
role hla;
pregnancy;
regulatory cells
Journal Title: American Journal of Reproductive Immunology
Year Published: 2020
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Journal Title: American Journal of Reproductive Immunology
Year Published: 2020
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!