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IL6, IL8, and IL10 in the distinction of malignant ovarian neoplasms and endometriomas

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Studies have shown a relationship between endometriosis and ovarian cancer. Our aims were to evaluate and compare the dosages of cytokines IL‐2, IL‐5, IL‐6, IL‐8, IL‐10, and TNF‐α in serum,… Click to show full abstract

Studies have shown a relationship between endometriosis and ovarian cancer. Our aims were to evaluate and compare the dosages of cytokines IL‐2, IL‐5, IL‐6, IL‐8, IL‐10, and TNF‐α in serum, intracystic fluid, and peritoneal fluid of patients with ovarian endometrioma, malignant and benign ovarian neoplasms, and non‐neoplastic ovarian tumors; to verify if there is a correlation between the values of these cytokines between ovarian endometrioma and ovarian malignancy; and to determine the best cut‐off point for serum cytokines that can be used to differentiate patients with ovarian malignancy and endometrioma.

Keywords: distinction malignant; il10 distinction; il6 il8; ovarian neoplasms; il8 il10; malignant ovarian

Journal Title: American Journal of Reproductive Immunology
Year Published: 2020

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