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Women with antiphospholipid antibodies (aPL) are at increased risk for pregnancy loss and preeclampsia. aPL target the trophoblast and induce a pro‐inflammatory, anti‐angiogenic and anti‐migratory profile. Since infection during pregnancy… Click to show full abstract
Women with antiphospholipid antibodies (aPL) are at increased risk for pregnancy loss and preeclampsia. aPL target the trophoblast and induce a pro‐inflammatory, anti‐angiogenic and anti‐migratory profile. Since infection during pregnancy can increase the risk for preeclampsia, a viral infection could further increase this in women with aPL. The goal of this study was to characterize the effect of viral components on trophoblast responses to aPL.
Keywords:
differentially modulated;
induced trophoblast;
antiphospholipid antibody;
responses differentially;
trophoblast responses;
antibody induced
Journal Title: American Journal of Reproductive Immunology
Year Published: 2021
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Journal Title: American Journal of Reproductive Immunology
Year Published: 2021
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!