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Progesterone modulates CD4+CD25+FoxP3+ regulatory T Cells and TGF‐β1 in the maternal‐fetal interface of the late pregnant mouse

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Progesterone supplementation is recommended to prevent spontaneous preterm birth (sPTB) in clinical practice. However, the exact mechanism is still unclear. This study aims to better understand the mechanisms that progesterone… Click to show full abstract

Progesterone supplementation is recommended to prevent spontaneous preterm birth (sPTB) in clinical practice. However, the exact mechanism is still unclear. This study aims to better understand the mechanisms that progesterone can prevent PTB.

Keywords: foxp3 regulatory; cd25 foxp3; cd4 cd25; modulates cd4; progesterone; progesterone modulates

Journal Title: American Journal of Reproductive Immunology
Year Published: 2022

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