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Expression of antimicrobial peptides in the amniotic fluid of women with cervical insufficiency

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Cervical insufficiency (CI) is associated with intra‐amniotic infection or inflammation. Antimicrobial peptides (AMPs) in amniotic fluid may protect the fetus against microbial invasion, giving their broad‐spectrum microbiocidal properties. We evaluated… Click to show full abstract

Cervical insufficiency (CI) is associated with intra‐amniotic infection or inflammation. Antimicrobial peptides (AMPs) in amniotic fluid may protect the fetus against microbial invasion, giving their broad‐spectrum microbiocidal properties. We evaluated changes in amniotic fluid AMP expression in women with CI and assessed whether these changes are related to their pregnancy outcomes.

Keywords: expression antimicrobial; amniotic fluid; cervical insufficiency; antimicrobial peptides

Journal Title: American Journal of Reproductive Immunology
Year Published: 2022

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