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The first case of ischemia‐free organ transplantation in humans: A proof of concept

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With great interest we have read the article by Xiaoshun He and colleagues regarding their first patient who underwent successful ischemia-free organ transplantation (IFOT).1 This group transplanted a liver donated… Click to show full abstract

With great interest we have read the article by Xiaoshun He and colleagues regarding their first patient who underwent successful ischemia-free organ transplantation (IFOT).1 This group transplanted a liver donated after brain death to a 51-year-old patient with decompensated cirrhosis and hepatocellular carcinoma without any ischemic episode or interruption of the blood circulation. The graft was procured, ex-situ preserved and implanted under continuous normothermic machine perfusion using the Liver Assist device (Organ Assist, Groningen, The Netherlands). The donor liver had 85-95% macrovesicular steatosis, however there was no post-reperfusion syndrome observed after revascularization of the graft and the recipient had an uneventful recovery. This article is protected by copyright. All rights reserved.

Keywords: free organ; organ transplantation; first case; transplantation; case ischemia; ischemia free

Journal Title: American Journal of Transplantation
Year Published: 2018

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