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Organ transplantation is limited due to the scarcity of donor organs. In order to expand the supply of organs for transplantation, interspecies chimeras have been examined as a potential future… Click to show full abstract
Organ transplantation is limited due to the scarcity of donor organs. In order to expand the supply of organs for transplantation, interspecies chimeras have been examined as a potential future source of humanized organs. Recent studies using gene editing technologies in combination with somatic cell nuclear transfer technology and hiPSCs successfully engineered humanized skeletal muscle in the porcine embryo. As these technologies progress, there are ethical issues that warrant consideration and dialogue.
Keywords:
humanized organs;
emerging technologies;
ethics exogenic;
chimeric humanized;
technologies ethics;
exogenic chimeric
Journal Title: American Journal of Transplantation
Year Published: 2022
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Journal Title: American Journal of Transplantation
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!