LAUSR

Our aim was to measure the ability of ischaemia‐modified albumin (IMA) to predict testicular histopathological damage in the testes of rats with short‐ and long‐term ischaemia using experimental testicular torsion and subsequent reperfusion via detorsion.21 Wistar Albino rats were randomized into three groups. The sham group was subjected to a mid‐scrotal incision only. The 4‐ and 8‐hr T/D (Torsion/Detorsion) groups were subjected to left testicular torsion by twisting the testes by 720 degrees counterclockwise. 2 cc venous blood samples were taken from the sham group after the mid‐scrotal incision, and from the 4‐ and 8‐hr T/D groups after 4 and 8 hr respectively. After that, the 4‐ and 8‐hr T/D groups were subjected to detorsion. Two days later, orchiectomy was performed. Ischaemia‐modified albumin levels were significantly different among the groups at 48 hr prior to orchiectomy (reperfusion; p = .003). Based on the results of the paired comparisons, it was found that IMA levels of the sham group were significantly higher than those of the 4‐ and 8‐hr T/D groups (p = .002 and .009 respectively). Our study has showed that IMA may be used to predict ischaemia/reperfusion injury, which is another complication that may occur following detorsion in testicular torsion.