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Effect and in silico characterization of genetic variants associated with severe spermatogenic disorders in a large Iberian cohort

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Severe spermatogenic failure (SpF) represents the most extreme manifestation of male infertility, as it decreases drastically the semen quality leading to either severe oligospermia (SO, Click to show full abstract

Severe spermatogenic failure (SpF) represents the most extreme manifestation of male infertility, as it decreases drastically the semen quality leading to either severe oligospermia (SO, <5 million spermatozoa/mL semen) or non‐obstructive azoospermia (NOA, complete lack of spermatozoa in the ejaculate without obstructive causes).

Keywords: silico characterization; genetic variants; effect silico; severe spermatogenic; characterization genetic; variants associated

Journal Title: Andrology
Year Published: 2021

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