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Previous studies in animal models evidenced that genetic mutations of KATNAL1, resulting in dysfunction of its encoded protein, lead to male infertility through disruption of microtubule remodelling and premature germ… Click to show full abstract
Previous studies in animal models evidenced that genetic mutations of KATNAL1, resulting in dysfunction of its encoded protein, lead to male infertility through disruption of microtubule remodelling and premature germ cell exfoliation. Subsequent studies in humans also suggested a possible role of KATNAL1 single‐nucleotide polymorphisms in the development of male infertility as a consequence of severe spermatogenic failure.
Keywords:
genetic variation;
common genetic;
variation katnal1;
infertility;
male infertility
Journal Title: Andrology
Year Published: 2022
Link to full text (if available)
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Journal Title: Andrology
Year Published: 2022
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!