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6‐nitrodopamine is a major endogenous modulator of human vas deferens contractility

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Rat isolated vas deferens releases 6‐nitrodopamine (6‐ND), and the spasmogenic activity of this novel catecholamine is significantly reduced by tricyclic compounds such as amitriptyline, desipramine, and carbamazepine and by antagonists… Click to show full abstract

Rat isolated vas deferens releases 6‐nitrodopamine (6‐ND), and the spasmogenic activity of this novel catecholamine is significantly reduced by tricyclic compounds such as amitriptyline, desipramine, and carbamazepine and by antagonists of the α1‐adrenergic receptors such as doxazosin, tamsulosin, and prazosin.

Keywords: vas deferens; endogenous modulator; nitrodopamine major; vas; modulator human; major endogenous

Journal Title: Andrology
Year Published: 2022

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