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Inhibition of multidrug resistance proteins by MK571 restored the erectile function in obese mice through cGMP accumulation

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Intracellular levels of cyclic nucleotides can also be controlled by the action of multidrug resistance protein types 4 (MRP4) and 5 (MRP5). To date, no studies evaluated the role of… Click to show full abstract

Intracellular levels of cyclic nucleotides can also be controlled by the action of multidrug resistance protein types 4 (MRP4) and 5 (MRP5). To date, no studies evaluated the role of their inhibition in an animal model of erectile dysfunction (ED).

Keywords: multidrug resistance; resistance proteins; inhibition multidrug; multidrug

Journal Title: Andrology
Year Published: 2022

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