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Adverse effects of levodopa/carbidopa intrajejunal gel treatment: A single‐center long‐term follow‐up study

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Levodopa/carbidopa intrajejunal gel (LCIG) is an effective therapeutic strategy to overcome levodopa‐induced motor complications in advanced Parkinson's disease (PD). However, it requires invasive percutaneous endoscopic gastrojejunostomy (PEG‐J) and may be… Click to show full abstract

Levodopa/carbidopa intrajejunal gel (LCIG) is an effective therapeutic strategy to overcome levodopa‐induced motor complications in advanced Parkinson's disease (PD). However, it requires invasive percutaneous endoscopic gastrojejunostomy (PEG‐J) and may be associated with serious adverse effects (AE). In this study, we aimed to evaluate long‐term AEs related to LCIG treatment in a large homogenous cohort of advanced PD patients.

Keywords: long term; intrajejunal gel; levodopa carbidopa; adverse effects; carbidopa intrajejunal

Journal Title: Acta Neurologica Scandinavica
Year Published: 2022

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