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SCN5A‐related Brugada syndrome (BrS) can be caused by multiple mechanisms including trafficking defects and altered channel gating properties. Most SCN5A mutations at pore region cause trafficking defects, and some of… Click to show full abstract
SCN5A‐related Brugada syndrome (BrS) can be caused by multiple mechanisms including trafficking defects and altered channel gating properties. Most SCN5A mutations at pore region cause trafficking defects, and some of them can be rescued by mexiletine (MEX).
Keywords:
reduced current;
current density;
rescued mexiletine;
brugada syndrome;
density partially
Journal Title: Annals of Noninvasive Electrocardiology
Year Published: 2021
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Journal Title: Annals of Noninvasive Electrocardiology
Year Published: 2021
Link to full text (if available)
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recommendations!