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Diagnostic inflammatory markers of acute cholangitis in liver transplant recipients

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Acute cholangitis (AC) after liver transplantation occurs in 8–12% patients and remains a significant cause of patients' morbidity and mortality. The 2018 Tokyo guidelines use white blood cell count and… Click to show full abstract

Acute cholangitis (AC) after liver transplantation occurs in 8–12% patients and remains a significant cause of patients' morbidity and mortality. The 2018 Tokyo guidelines use white blood cell count and C‐reactive protein (CRP) as diagnostic criteria in AC. However, these and other common inflammatory markers have not been assessed in immunosuppressed liver transplant (LT) recipients with AC. The aims of this study were to compare the discriminative powers of common inflammatory markers, define the best inflammatory marker and determine the diagnostic cut‐off values for the inflammatory markers in LT recipients with AC.

Keywords: acute cholangitis; liver; liver transplant; inflammatory markers; transplant recipients; cholangitis liver

Journal Title: ANZ Journal of Surgery
Year Published: 2020

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