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Surgical management of familial pancreatic cancer: a systematic review of the literature

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Pancreatic ductal adenocarcinoma (PDAC) is the third most common cause of cancer‐related mortality. The fact that the vast majority of patients with PDAC are diagnosed at an advanced stage highlights… Click to show full abstract

Pancreatic ductal adenocarcinoma (PDAC) is the third most common cause of cancer‐related mortality. The fact that the vast majority of patients with PDAC are diagnosed at an advanced stage highlights the need of early diagnosis. As hereditary factors are associated with approximately 5% of all PDAC cases, a screening programme to these high‐risk individuals (HRI) has been proposed. The aim of screening methods is to identify selected group of patients with morphological abnormalities at an early stage, in order to be treated promptly. In this study, we evaluate the surgical outcomes and the appropriateness of pancreatic resection in HRIs who were selected for screening.

Keywords: pancreatic cancer; management familial; familial pancreatic; cancer systematic; surgical management; cancer

Journal Title: ANZ Journal of Surgery
Year Published: 2022

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