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Elevated nitric oxide in recurrent vulvovaginal candidiasis – association with clinical findings

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Recurrent vulvovaginal candidiasis is defined as having three to four episodes per year and causes substantial suffering. Little is known about the mechanisms leading to relapses in otherwise healthy women.… Click to show full abstract

Recurrent vulvovaginal candidiasis is defined as having three to four episodes per year and causes substantial suffering. Little is known about the mechanisms leading to relapses in otherwise healthy women. Nitric oxide is part of the nonspecific host defense and is increased during inflammation. Nitric oxide levels were measured and the expression of inducible nitric oxide synthase was analyzed in the vagina during an acute episode of recurrent vulvovaginal candidiasis and after treatment with fluconazole.

Keywords: recurrent vulvovaginal; elevated nitric; vulvovaginal candidiasis; oxide recurrent; nitric oxide

Journal Title: Acta Obstetricia et Gynecologica Scandinavica
Year Published: 2017

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