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Following targeted routine antenatal anti‐D prophylaxis, almost half of the pregnant women had undetectable anti‐D prophylaxis at delivery

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In September 2016, a nationwide targeted routine antenatal anti‐D prophylaxis program was implemented in Norway. The prophylaxis (anti‐D immunoglobulin) aims to cover the whole third trimester and is administered in… Click to show full abstract

In September 2016, a nationwide targeted routine antenatal anti‐D prophylaxis program was implemented in Norway. The prophylaxis (anti‐D immunoglobulin) aims to cover the whole third trimester and is administered in gestational week 28 to RhD‐negative women who carry RhD‐positive fetuses. However, in many women, antibody screening at delivery does not detect anti‐D immunoglobulin. The goal of this study was to investigate the presumable role of dose and timing of antenatal anti‐D immunoglobulin administration in non‐detectable prophylaxis at the time of delivery.

Keywords: targeted routine; anti prophylaxis; antenatal anti; routine antenatal; prophylaxis; delivery

Journal Title: Acta Obstetricia et Gynecologica Scandinavica
Year Published: 2022

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