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Translation of hyaluronic acid–based vitreous substitutes towards current regulations for medical devices

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Hydrogel‐based vitreous substitutes have the potential to overcome the limitations of current clinically used endotamponades. With the goal of entering clinical trials, the present study aimed to (I) transfer the… Click to show full abstract

Hydrogel‐based vitreous substitutes have the potential to overcome the limitations of current clinically used endotamponades. With the goal of entering clinical trials, the present study aimed to (I) transfer the material synthesis of hyaluronic acid–based hydrogels into a routine, pharmaceutical‐appropriate production and (II) evaluate the properties of the vitreous substitutes in terms of the current regulations for medical devices (MDR/ISO standards).

Keywords: based vitreous; vitreous substitutes; current regulations; acid based; regulations medical; hyaluronic acid

Journal Title: Acta Ophthalmologica
Year Published: 2022

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