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Accumulating evidence suggests that orexin signalling is involved in the regulation of blood pressure and cardiovascular function. However, the underlying mechanisms are not clear. Here, we test the hypothesis that… Click to show full abstract
Accumulating evidence suggests that orexin signalling is involved in the regulation of blood pressure and cardiovascular function. However, the underlying mechanisms are not clear. Here, we test the hypothesis that upregulated orexin A signalling in the paraventricular nucleus (PVN) increases sympathetic nerve activity (SNA) through stimulating expression of proinflammatory cytokines (PICs).
Keywords:
increases sympathetic;
proinflammatory cytokines;
expression proinflammatory;
nerve activity;
sympathetic nerve
Journal Title: Acta Physiologica
Year Published: 2018
Link to full text (if available)
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Journal Title: Acta Physiologica
Year Published: 2018
Link to full text (if available)
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recommendations!