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Perinatal free‐choice of a high‐calorie low‐protein diet affects leptin signaling through IRS1 and AMPK dephosphorylation in the hypothalami of female rat offspring in adulthood

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We aimed to investigate whether a dysregulated maternal diet during gestation and lactation induces long‐lasting changes in the hypothalamic control of feeding behavior in the offspring and whether this effect… Click to show full abstract

We aimed to investigate whether a dysregulated maternal diet during gestation and lactation induces long‐lasting changes in the hypothalamic control of feeding behavior in the offspring and whether this effect is sex specific.

Keywords: free choice; low protein; choice high; perinatal free; high calorie; calorie low

Journal Title: Acta Physiologica
Year Published: 2019

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