LAUSR

The circadian brain and body clocks are essential to human health and wellbeing. Misaligned or disrupted clocks are common in modern society and are associated with numerous, highly prevalent, population diseases such as metabolic syndromes, cancer, psychiatric disorder and cardiovascular pathologies. Moreover, time-of-day adapted therapy (chronotherapy) has often been proven to be superior over standard therapy. Within just a few years, a new innovative (sub-) field of physiology and medicine has emerged - chronomedicine, which has greatly improved our understanding of the role of internal clocks for health and disease. However, until recently, one key barrier prevented widespread adoption of time-of-day dependent therapeutic approaches, i.e. the lack of an easy diagnostic assay for measuring internal time in humans. This article is protected by copyright. All rights reserved.