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The skeletal muscle Cl− channels, the ClC‐1 channels, stabilize the resting membrane potential and dampen muscle fibre excitability. This study explored whether ClC‐1 inhibition can recover nerve‐stimulated force in isolated… Click to show full abstract
The skeletal muscle Cl− channels, the ClC‐1 channels, stabilize the resting membrane potential and dampen muscle fibre excitability. This study explored whether ClC‐1 inhibition can recover nerve‐stimulated force in isolated muscle under conditions of compromised neuromuscular transmission akin to disorders of myasthenia gravis and Lambert–Eaton syndrome.
Keywords:
inhibition improves;
inhibition;
channel inhibition;
chloride channel;
improves neuromuscular;
neuromuscular function
Journal Title: Acta Physiologica
Year Published: 2021
Link to full text (if available)
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Journal Title: Acta Physiologica
Year Published: 2021
Link to full text (if available)
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recommendations!