"HDAC3 inhibition improves urinary‐concentrating defect in hypokalaemia by promoting AQP2 transcription"

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This study investigated whether enhanced histone acetylation, achieved by inhibiting histone deacetylases (HDACs), could prevent decreased aquaporin‐2 (AQP2) expression during hypokalaemia. Click to show full abstract

This study investigated whether enhanced histone acetylation, achieved by inhibiting histone deacetylases (HDACs), could prevent decreased aquaporin‐2 (AQP2) expression during hypokalaemia.

Keywords: inhibition improves; hdac3 inhibition; hypokalaemia; concentrating defect; urinary concentrating; improves urinary

Journal Title: Acta Physiologica
Year Published: 2022

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