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Dynorphin promotes stress‐induced depressive behaviors by inhibiting ventral pallidal neurons in rats

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Endogenous dynorphin signaling via kappa opioid receptors (KORs) plays a key role in producing the depressive and aversive consequences of stress. We investigated the behavioral effects of the dynorphin/KOR system… Click to show full abstract

Endogenous dynorphin signaling via kappa opioid receptors (KORs) plays a key role in producing the depressive and aversive consequences of stress. We investigated the behavioral effects of the dynorphin/KOR system in the ventral pallidum (VP) and studied the underlying mechanisms.

Keywords: promotes stress; depressive behaviors; induced depressive; stress induced; dynorphin promotes; behaviors inhibiting

Journal Title: Acta Physiologica
Year Published: 2022

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