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Intramural Purkinje fibers facilitate rapid ventricular activation in the equine heart

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The Purkinje fibers convey the electrical impulses at much higher speed than the working myocardial cells. Thus, the distribution of the Purkinje network is of paramount importance for the timing… Click to show full abstract

The Purkinje fibers convey the electrical impulses at much higher speed than the working myocardial cells. Thus, the distribution of the Purkinje network is of paramount importance for the timing and coordination of ventricular activation. The Purkinje fibers are found in the subendocardium of all species of mammals, but some mammals also possess an intramural Purkinje fiber network that provides for relatively instantaneous, burst‐like activation of the entire ventricular wall, and gives rise to an rS configuration in lead II of the ECG.

Keywords: intramural purkinje; ventricular activation; purkinje; fibers facilitate; purkinje fibers

Journal Title: Acta Physiologica
Year Published: 2023

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