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To clarify the hypothesis tests associated with the full covariate modelling (FCM) approach in population pharmacokinetic analysis, investigate the potential impact of multiplicity in population pharmacokinetic analysis, and evaluate simultaneous… Click to show full abstract
To clarify the hypothesis tests associated with the full covariate modelling (FCM) approach in population pharmacokinetic analysis, investigate the potential impact of multiplicity in population pharmacokinetic analysis, and evaluate simultaneous confidence intervals (SCI) as an approach to control multiplicity.
Keywords:
full covariate;
hypothesis tests;
approach population;
covariate modelling;
approach;
population
Journal Title: British Journal of Clinical Pharmacology
Year Published: 2018
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Journal Title: British Journal of Clinical Pharmacology
Year Published: 2018
Link to full text (if available)
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recommendations!