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Accurately estimating kidney function is essential for the safe administration of renally cleared drugs such as ganciclovir. Current practice recommends adjusting renally eliminated drugs according to the Cockcroft–Gault equation. There… Click to show full abstract
Accurately estimating kidney function is essential for the safe administration of renally cleared drugs such as ganciclovir. Current practice recommends adjusting renally eliminated drugs according to the Cockcroft–Gault equation. There are no data on the utility of the Modification of Diet in Renal Disease (MDRD) and Chronic Kidney Disease Epidemiology Collaboration (CKD‐EPI) equations in ganciclovir dosing. To evaluate which renal function equation best predicts ganciclovir clearance.
Journal Title: British Journal of Clinical Pharmacology
Year Published: 2018
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