"Development of a physiologically based pharmacokinetic model for mefloquine and its application alongside a clinical effectiveness model to select an optimal dose for prevention of malaria in young Caucasian children"

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Development of a physiologically based pharmacokinetic model for mefloquine and its application alongside a clinical effectiveness model to select an optimal dose for prevention of malaria in young Caucasian children

To predict the optimal chemoprophylactic dose of mefloquine in infants of 5–10 kg using physiologically based pharmacokinetic (PBPK) and clinical effectiveness models. Click to show full abstract

To predict the optimal chemoprophylactic dose of mefloquine in infants of 5–10 kg using physiologically based pharmacokinetic (PBPK) and clinical effectiveness models.

Keywords: based pharmacokinetic; clinical effectiveness; physiologically based; model; mefloquine

Journal Title: British Journal of Clinical Pharmacology
Year Published: 2019

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