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Carboplatin dosage is calculated by using the estimated glomerular filtration rate (GFR) to achieve a target plasma area under the plasma concentration–time curve (AUC). The aims of the present study… Click to show full abstract
Carboplatin dosage is calculated by using the estimated glomerular filtration rate (GFR) to achieve a target plasma area under the plasma concentration–time curve (AUC). The aims of the present study were to investigate factors that influence the pharmacokinetics of carboplatin in children with high‐risk neuroblastoma, and whether target exposures for carboplatin were achieved using current treatment protocols.
Keywords:
etoposide melphalan;
melphalan children;
children evaluation;
population pharmacokinetics;
pharmacokinetics carboplatin;
carboplatin etoposide
Journal Title: British Journal of Clinical Pharmacology
Year Published: 2019
Link to full text (if available)
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Journal Title: British Journal of Clinical Pharmacology
Year Published: 2019
Link to full text (if available)
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recommendations!