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Demonstrate the presence of cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT) proteins and mRNAs in isolated human plasma exosomes and evaluate the capacity for exosome‐derived biomarkers to characterize variability in CYP3A4… Click to show full abstract
Demonstrate the presence of cytochrome P450 (CYP) and UDP‐glucuronosyltransferase (UGT) proteins and mRNAs in isolated human plasma exosomes and evaluate the capacity for exosome‐derived biomarkers to characterize variability in CYP3A4 activity.
Keywords:
characterize variability;
plasma extracellular;
drug;
derived biomarkers;
exosome derived
Journal Title: British Journal of Clinical Pharmacology
Year Published: 2019
Link to full text (if available)
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Journal Title: British Journal of Clinical Pharmacology
Year Published: 2019
Link to full text (if available)
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recommendations!