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Bioequivalence of macitentan and tadalafil given as fixed‐dose combination or single‐component tablets in healthy subjects

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To demonstrate the bioequivalence of macitentan/tadalafil fixed‐dose combination (FDC) tablets with single‐component tablets of macitentan and tadalafil in healthy subjects. Click to show full abstract

To demonstrate the bioequivalence of macitentan/tadalafil fixed‐dose combination (FDC) tablets with single‐component tablets of macitentan and tadalafil in healthy subjects.

Keywords: dose combination; tadalafil; macitentan tadalafil; single component; fixed dose; bioequivalence macitentan

Journal Title: British Journal of Clinical Pharmacology
Year Published: 2020

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