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Evaluation of drug interaction potential of zanubrutinib with cocktail probes representative of CYP3A4, CYP2C9, CYP2C19, P‐gp and BCRP

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This study aims to assess the potential effects of zanubrutinib on the activity of cytochrome P450 (CYP) enzymes and drug transporter proteins using a cocktail probe approach. Click to show full abstract

This study aims to assess the potential effects of zanubrutinib on the activity of cytochrome P450 (CYP) enzymes and drug transporter proteins using a cocktail probe approach.

Keywords: drug interaction; evaluation drug; interaction potential; drug; cocktail; potential zanubrutinib

Journal Title: British Journal of Clinical Pharmacology
Year Published: 2020

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