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Triple antithrombotic therapy and dual therapy – What is the evidence base?

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A 78-year-old woman with atrial fibrillation (AF) and hypertension presented to the emergency department with chest pain. Her medications include amlodipine 5 mg once daily and apixaban 5 mg twice… Click to show full abstract

A 78-year-old woman with atrial fibrillation (AF) and hypertension presented to the emergency department with chest pain. Her medications include amlodipine 5 mg once daily and apixaban 5 mg twice daily. The admission ECG demonstrated T-wave changes in the lateral leads with a raised troponin (200 ng/L [cut-off 14 ng/L]) consistent with a non-ST segment elevation myocardial infarction (NSTEMI). She was reviewed by the local cardiologist and an invasive treatment strategy was selected. She was subsequently treated with aspirin/clopidogrel and treatment dose anticoagulation.

Keywords: triple antithrombotic; therapy; dual therapy; therapy evidence; antithrombotic therapy; therapy dual

Journal Title: British Journal of Clinical Pharmacology
Year Published: 2022

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