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Pharmacokinetic and pharmacodynamic interaction of DWP16001, a sodium–glucose cotransporter 2 inhibitor, with gemigliptin and metformin in healthy adults

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DWP16001, a novel sodium–glucose cotransporter 2 inhibitor, is under clinical development for the treatment of type 2 diabetes mellitus. This study aimed to explore the pharmacokinetics (PK) and pharmacodynamics interaction… Click to show full abstract

DWP16001, a novel sodium–glucose cotransporter 2 inhibitor, is under clinical development for the treatment of type 2 diabetes mellitus. This study aimed to explore the pharmacokinetics (PK) and pharmacodynamics interaction of DWP16001 with gemigliptin and metformin.

Keywords: cotransporter inhibitor; glucose cotransporter; gemigliptin metformin; dwp16001; interaction dwp16001; sodium glucose

Journal Title: British Journal of Clinical Pharmacology
Year Published: 2022

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