Pre‐emptive prediction to avoid myelosuppression and harmful sequelae is difficult given the complex interplay among patients, drugs and treatment protocols. This study aimed to model plasma and bone marrow concentrations… Click to show full abstract
Pre‐emptive prediction to avoid myelosuppression and harmful sequelae is difficult given the complex interplay among patients, drugs and treatment protocols. This study aimed to model plasma and bone marrow concentrations and the likelihood of myelotoxicity following administration of 5‐fluorouracil (5‐FU) by diverse intravenous (IV) bolus or continuous infusion (cIF) regimens.
Keywords:
myelotoxicity;
continuous infusion;
intravenous bolus;
administration mode
Journal Title: British Journal of Clinical Pharmacology
Year Published: 2024
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!
Journal Title: British Journal of Clinical Pharmacology
Year Published: 2024
Link to full text (if available)
Share on Social Media: Sign Up to like & get
recommendations!