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A mood state‐specific interaction between kynurenine metabolism and inflammation is present in bipolar disorder

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Cytokines are thought to contribute to the pathogenesis of psychiatric symptoms by kynurenine pathway activation. Kynurenine metabolites affect neurotransmission and can cause neurotoxicity. We measured inflammatory markers in patients with… Click to show full abstract

Cytokines are thought to contribute to the pathogenesis of psychiatric symptoms by kynurenine pathway activation. Kynurenine metabolites affect neurotransmission and can cause neurotoxicity. We measured inflammatory markers in patients with bipolar disorder (BD) and studied their relation to kynurenine metabolites and mood.

Keywords: kynurenine; mood state; state specific; specific interaction; bipolar disorder

Journal Title: Bipolar Disorders
Year Published: 2019

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