LAUSR.org creates dashboard-style pages of related content for over 1.5 million academic articles. Sign Up to like articles & get recommendations!

Rejoinder: A formal causal interpretation of the case-crossover design.

Photo by 90angle from unsplash

We thank the discussants for their insightful commentary and questions. In our rejoinder, we extend our analysis to additional settings, control strategies, and sources of bias relevant to how case-crossover… Click to show full abstract

We thank the discussants for their insightful commentary and questions. In our rejoinder, we extend our analysis to additional settings, control strategies, and sources of bias relevant to how case-crossover is often used in practice, as suggested by multiple discussants. In particular, we consider: control exposures that follow occurrence of events, settings with shared exposure trajectories (which are common in case-crossover studies of effects of air pollution), bias due to non-transient treatment effects, removing bias due to time trends in treatment using control subjects, and extending our results to the continuous time setting. We also take the opportunity to clarify an easily misinterpreted comment we made about collapsibility, which we thank Andersen and Martinussen for highlighting. Throughout, in the spirit of the discussants. contributions, we iterate between general bias formulas and simulations and numerical studies from illustrative simplified scenarios to build insight.

Keywords: case crossover; rejoinder formal; causal interpretation; case; formal causal

Journal Title: Biometrics
Year Published: 2022

Link to full text (if available)


Share on Social Media:                               Sign Up to like & get
recommendations!

Related content

More Information              News              Social Media              Video              Recommended



                Click one of the above tabs to view related content.