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Clinical signs associated with an increased risk of interstitial lung disease: a retrospective study of 101 patients with dermatomyositis

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Pulmonary complications are common in dermatomyositis (DM) and contribute to significant morbidity and mortality1-3. Patients with dermatomyositis and anti-synthethase4, anti-PM/Scl5 or anti-MDA56 antibodies have specific signs (mechanic's hands in anti-synthethase… Click to show full abstract

Pulmonary complications are common in dermatomyositis (DM) and contribute to significant morbidity and mortality1-3. Patients with dermatomyositis and anti-synthethase4, anti-PM/Scl5 or anti-MDA56 antibodies have specific signs (mechanic's hands in anti-synthethase phenotype; skin and oral ulcers, arthritis and arthralgia, and alopecia in anti-MDA5 phenotype and sclerodermatous changes in anti-PM/Scl phenotype) and an increased risk of interstitial lung disease (ILD). This article is protected by copyright. All rights reserved.

Keywords: increased risk; lung disease; patients dermatomyositis; interstitial lung; risk interstitial

Journal Title: British Journal of Dermatology
Year Published: 2017

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