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Atopic dermatitis is associated with reduced corneodesmosin expression: role of cytokine modulation and effects on viral penetration

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The skin epidermal barrier plays a critical role in preventing allergen and microbial penetration into the human body.1 Atopic dermatitis (AD) is characterized by epidermal barrier defects and recurrent microbial… Click to show full abstract

The skin epidermal barrier plays a critical role in preventing allergen and microbial penetration into the human body.1 Atopic dermatitis (AD) is characterized by epidermal barrier defects and recurrent microbial skin infections.1 Recent studies indicate that defects in epidermal barrier function contribute greatly to the initiation and perpetuation of skin inflammation in AD.2 This article is protected by copyright. All rights reserved.

Keywords: atopic dermatitis; epidermal barrier; role; penetration

Journal Title: British Journal of Dermatology
Year Published: 2017

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