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Maintenance phase in psoralen–ultraviolet A phototherapy of early‐stage mycosis fungoides. A critically appraised topic

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A 65‐year‐old patient affected by mycosis fungoides (MF) stage IB achieved complete remission (CR) after a cycle of PUVA phototherapy. The U.S. Cutaneous Lymphoma Consortium (USCLC) guidelines suggest that the… Click to show full abstract

A 65‐year‐old patient affected by mycosis fungoides (MF) stage IB achieved complete remission (CR) after a cycle of PUVA phototherapy. The U.S. Cutaneous Lymphoma Consortium (USCLC) guidelines suggest that the patient should be kept in the maintenance phase, defined as a ‘period of gradual decrease of frequency of UVL [ultraviolet light] while in clinical remission before discontinuation of phototherapy’ by slowly tapering the number of psoralen–ultraviolet A (PUVA) applications over time up to clinical relapse. The USCLC guidelines also suggest a standardized schedule for the maintenance phase. Alternatively, the patient could end PUVA therapy and go straight to follow‐up.

Keywords: maintenance; mycosis fungoides; maintenance phase; psoralen ultraviolet

Journal Title: British Journal of Dermatology
Year Published: 2017

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