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Oral mucosa is a useful substrate for detecting autoantibodies of mucous membrane pemphigoid

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Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease targeting various autoantigens, including the C-terminus of collagen XVII (COL17) and laminin332. Bullous pemphigoid (BP) is the most common autoimmune… Click to show full abstract

Mucous membrane pemphigoid (MMP) is a rare autoimmune blistering disease targeting various autoantigens, including the C-terminus of collagen XVII (COL17) and laminin332. Bullous pemphigoid (BP) is the most common autoimmune blistering disease, affecting the mucosae in 10-20% of cases. COL17, particularly, the non-collagenous (NC)16A domain is the pathogenic epitope for BP. This article is protected by copyright. All rights reserved.

Keywords: membrane pemphigoid; mucosa useful; useful substrate; mucous membrane; oral mucosa

Journal Title: British Journal of Dermatology
Year Published: 2018

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