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Desmoplakin (DSP) is a cytolinker of the plakin family. It mediates the connection of intermediate filaments (IFs) to desmosomes, intercellular adhesion junctions. The carboxyl (C)-terminal tail of DSP binds to… Click to show full abstract
Desmoplakin (DSP) is a cytolinker of the plakin family. It mediates the connection of intermediate filaments (IFs) to desmosomes, intercellular adhesion junctions. The carboxyl (C)-terminal tail of DSP binds to IFs, while its amino-terminal part interacts with the armadillo proteins plakophilins and plakoglobin that in turn associate with the desmosomal cadherin desmogleins and desmocollins1 . This article is protected by copyright. All rights reserved.
Keywords:
gene linked;
recessive mutation;
linked cardiomyopathy;
mutation dsp;
dsp;
dsp gene
Journal Title: British Journal of Dermatology
Year Published: 2018
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Journal Title: British Journal of Dermatology
Year Published: 2018
Link to full text (if available)
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recommendations!