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Combined culture and metagenomic analyses reveal significant shifts in the composition of the cutaneous microbiome in psoriasis

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The treatment of psoriasis has been revolutionized by the development of biologic therapies. However, the pathogenesis of psoriasis, in particular the role of the cutaneous microbiome, remains incompletely understood. Moreover,… Click to show full abstract

The treatment of psoriasis has been revolutionized by the development of biologic therapies. However, the pathogenesis of psoriasis, in particular the role of the cutaneous microbiome, remains incompletely understood. Moreover, skin microbiome studies have relied heavily on 16S rRNA sequencing data in the absence of bacterial culture.

Keywords: culture metagenomic; cutaneous microbiome; metagenomic analyses; psoriasis; combined culture

Journal Title: British Journal of Dermatology
Year Published: 2019

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