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Substance P and neurokinin 1 receptor are new targets for the treatment of chronic pruritus

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Chronic pruritus is a distressing symptom associated with various dermatological conditions and systemic diseases. Current treatment options are often inadequate, resulting in impaired quality of life for many patients. An… Click to show full abstract

Chronic pruritus is a distressing symptom associated with various dermatological conditions and systemic diseases. Current treatment options are often inadequate, resulting in impaired quality of life for many patients. An understanding of the underlying mechanisms of itch across pruritic conditions is important for development of effective, targeted treatments for chronic pruritus.

Keywords: neurokinin receptor; substance neurokinin; receptor new; treatment; pruritus; chronic pruritus

Journal Title: British Journal of Dermatology
Year Published: 2019

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