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The role of misclassification of exposure in the association between aspirin and nonsteroidal anti‐inflammatory drug use and keratinocyte cancers

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We read with interest the recently published paper by Pandeya et al.1 , which assessed the association between aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) and incident keratinocyte cancers (KC) in a… Click to show full abstract

We read with interest the recently published paper by Pandeya et al.1 , which assessed the association between aspirin and non-steroidal anti-inflammatory drugs (NSAIDs) and incident keratinocyte cancers (KC) in a cohort study and reported a weak and inconsistent association between aspirin and NSAID use and KC. However, this study design and especially exposure definition, i.e. extent of aspirin and NSAID use, may have led to misclassification of exposure, and thereby to biased results. This article is protected by copyright. All rights reserved.

Keywords: anti inflammatory; association aspirin; misclassification exposure; use; keratinocyte cancers; association

Journal Title: British Journal of Dermatology
Year Published: 2019

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