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The clinical presentation and pathology of discoid lupus erythematosus (DLE) varies by stage. Erythematous scaly papules and plaques characterize the early lesions. They progress to dyspigmented patches and plaques with… Click to show full abstract
The clinical presentation and pathology of discoid lupus erythematosus (DLE) varies by stage. Erythematous scaly papules and plaques characterize the early lesions. They progress to dyspigmented patches and plaques with central scarring and atrophy. Under histology, early lesions demonstrate a perivascular and perifollicular inflammatory infiltrate, liquefactive degeneration and keratinocyte apoptosis. Increased collagen deposition within the dermis and reduced inflammatory infiltrate is seen in later stages [1].
Journal Title: British Journal of Dermatology
Year Published: 2019
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