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Dimethyl fumarate modulates the Treg–Th17 cell axis in patients with psoriasis *

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Dimethyl fumarate (DMF) is the active ingredient of Skilarence™ and Tecfidera™, which are used for the treatment of psoriasis and multiple sclerosis, respectively. Various immunomodulatory mechanisms of action have been… Click to show full abstract

Dimethyl fumarate (DMF) is the active ingredient of Skilarence™ and Tecfidera™, which are used for the treatment of psoriasis and multiple sclerosis, respectively. Various immunomodulatory mechanisms of action have been identified for DMF; however, it is still unclear what effects DMF exerts in vivo in patients with psoriasis.

Keywords: patients psoriasis; treg th17; fumarate modulates; modulates treg; dimethyl fumarate

Journal Title: British Journal of Dermatology
Year Published: 2020

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