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Adamantiades-Behçet's disease (ABD; MIM 109650) is a rare, neutrophilic vascular reaction or vasculitis with a chronic recurrent progressive course leading to systemic inflammatory vascular disease with potentially severe prognosis.1 Its… Click to show full abstract
Adamantiades-Behçet's disease (ABD; MIM 109650) is a rare, neutrophilic vascular reaction or vasculitis with a chronic recurrent progressive course leading to systemic inflammatory vascular disease with potentially severe prognosis.1 Its aetiology remains unknown. A genetic predisposition, triggered by infection/environmental factor(s) leading to hyperergic immunological reaction/damage of the vascular endothelium is assumed. A responsible gene locus is probably located on chromosome 6 short arm (6p21.3) inside the major histocompatibility complex area.
Journal Title: British Journal of Dermatology
Year Published: 2020
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